Job Description

Job Description

The Role:
Title: In vivo research associate, Immunology and Pharmacology

Job summary:
The PharmaEssentia Innovation Research Center is building a world-class new drug discovery team in Boston area. We are seeking a highly motivated in vivo research associate to support in vivo experiment (rodent), including MTD studies, Efficacy studies, PK/PD studies and tissue harvest. You will also be asked to maintain and expand cancer cell lines to support the in vivo tumor model studies and conduct hand-on dosing and procedure support for mice pharmacology studies. In addition, you may need to support all aspects of laboratory operation to maintain a highly productive vivarium/laboratory.

The Company:
It’s not often that you get the chance to make a real impact on the lives of others, while expanding your own possibilities. You’ll find that rare opportunity at PharmaEssentia. Join us, and let’s transform lives, together.
PharmaEssentia Corporation is a rapidly growing biopharmaceutical innovator. We are leveraging deep expertise and proven scientific principles to deliver effective new biologics for challenging diseases in the areas of hematology, oncology and immunology, with one approved product and a diversifying pipeline. We believe in the potential to improve both the health and quality of life for patients with limited options today through the combination of rigorous research and innovative thinking.
Founded in 2003 by a team of Taiwanese American executives and renowned scientists from U.S. biotechnology and pharmaceutical companies, today we are listed on the Taipei Exchange (TPEx: 6446) and are expanding our global presence with operations in the U.S., Japan, China and Korea, along with a world-class biologics production facility in Taichung.
Our new research center, PharmaEssentia Innovation Research Center (PIRC), aims to leverage our current expertise in oncology and immunology therapeutic areas to identify and develop novel therapeutic opportunities. Therefore, we are recruiting talented scientists who have deep knowledge in immunology, translational science, bioinformatics and biologics platforms to develop novel drugs through disease-driving biology, novel technology in protein engineering, antibody discovery and new modalities.

PIRC offers a competitive benefit package, including a competitive 401k match, medical/dental/eye care benefits, and other benefits.

Summary of Key Responsibilities:

• Hand-on execute subcutaneous tumor model studies from cancer cells expansion, implantation (in mice), tumor measurement, group randomization and administration of test articles.
• Hand-on support all mice pharmacology study procedures, including but not limiting to dosing and tissue harvest.
• Follow PIRC IACUC program/protocols and standard operating procedures (SOPs) for all animal procedures.
• Maintain and expand cancer cell lines for human xenograft tumor and mouse syngeneic tumor models.
• Ensure day-to-day animal welfare, environmental quality, supply logistics, work scheduling, training, and performance management of the animal caretaking team.
• Data process and graphing for the internal team update presentation.

Essential Qualifications:

• B.S. or higher degree in immunology, pharmaceutical sciences or related scientific field

  Skill

Performed in the last 2 years
(includes training)

In vitro assay

ELISA

Not required, good to know

MSD

Not required, good to know

FACS

Not required, good to know

Husbandry

Aseptic Technique

Must

Micro-Isolator Technique

Must

Restraint & Handling

Must

Room Checks

Not required, good to know

Cage Change

Not required, good to know

Injections/ Administration

Subcutaneous

Must

Intraperitoneal

Must

Intravenous

Must

Intramuscular

Not required

Oral Gavage

Not required, good to know

Blood Withdrawal

Tail Bleed

Must

Cardiac Puncture

Must

Submandibular

Must

RO Bleed

Not required, good to know

Euthanasia

CO 2 Overdose

Must

Cervical Dislocation

Must

Decapitation

Not required

Animal Preparation

Shaving

Must

Ear Tagging

Not required

Ear Punching/ Notching

Not required

Implantation

Xenograft SC

Must

Mammary Fat Pad

Good to know

Trocar

Not required

Anesthesia

Isoflurane Anesthesia

Not required, good to know

Lab Operations

General Organizing lab space

Must

Receiving/stocking supplies

Must

Any other duties that may arise

Must

Mammalian Cell Culture

Standard mammalian cell culture procedures and associated aseptic techniques in addition to maintenance of tissue culture facilities

Must

Media and buffer preparation, culture initiation, propagation, and cryopreservation of cells, including primary human and mouse cells and cell lines as well as adherence to quality control schedules for ensuring consistency of cell culture materials.

Must

 

EEO Statement:
At PharmaEssentia Innovation Research Center (PIRC), we are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law. PIRC believes that diversity and inclusion among our team are critical to our success as a global company, and we seek to recruit, develop and retain the most talented people from a diverse candidate pool.  PIRC does not accept unsolicited agency resumes. Staffing agencies should not send resumes to our HR team or to any PIRC employees. PIRC is not responsible for any fees related to unsolicited resumes from staffing agencies.

 

At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer.

Job Tags

Full time,

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